Cimetidine is a regularly used medicine to treat stomach problems. The affect with this drugs are to stop the creation of stomach acid. One example of these conditions is referred to as gastroesophageal reflux disease and it is the retrograde movement of stomach contents from your stomach back up in the oesophagus which inflames the lining of the oesophagus resulting in indigestion which is more frequently called heartburn, especially soon after bedtime. It may also result in a sour or unpleasant taste in the mouth. This can impact nearly 10-20% of people. There are numerous risk factors that raise the possibility of this happening, and they all ought to be taken care of in the long run to deal with the issue. For the short term, it could make sense to minimize how much of the gastric acid is produced to decrease the symptoms. That is where cimetidine comes into play. Cimetidine inhibits receptors in the tissue of the gastric lining which will prevents gastric acid secretion. Which means that there is less stomach acid to irritate the oesophagus and cause the symptoms. Cimetidine is familiar in the name brand, Tagamet coming from pharmaceutical firm Glaxosmithkline Inc, however there are several other less well known brands available. It was first sold in 1976 and soon became the first of the so-called ‘blockbuster’ drug treatments and making a significant profit for the business. It was originally a prescription only pharmaceutical but it currently is accessible as an over-the-counter drugs without having a prescription. The drug is not utilized as much today as it was previously as different medication have been introduced which commonly give you a improved end result for the gastroesophageal reflux disease such as omeprazole that works as a proton pump inhibitor.
During the 90’s cimetidine started to be strongly suggested for many dermatological disorders for example warts or verruca that are caused by a virus infection. The advisable dosage from the ones that endorse its use is to take 40 mg/kg/day, however please check with a health care professional first. The supposed mechanism with this could be that the medicine boosts the immune system and a couple of studies have shown there were increased levels of biomarkers of immune activation in the skin of those who had warts which did get better. There have been a lot of testimonials that warts or verruca going away when using this drug. There initially were a few early scientific studies that didn’t use a control group which demonstrated it appeared very effective at treating warts. However , verruca often go away by themselves eventually (that could be quite a while) and are frequently quite responsive to a placebo. The question has to be asked does cimetidine for verruca work or perhaps is it really an expensive placebo. Recently research has been done with control groups that were blinded and provided a placebo believing it had been the medicine and unfortunately revealed that using Tagamet for verruca isn’t any better than using a placebo. Should you have warts or verrucae, then obtain help and advice from a health care professional concerning your best therapy selection.
For more on cimetidine:
How a common antacid could lead to cheaper anti-cancer drugs
Article by: Craig Payne August 1, 2022